CSF Amino Acids, Pterins and Mechanism of the Ketogenic Diet
نویسنده
چکیده
Investigators from Hospital Sant Joan de Deu, Barcelona, Spain, studied the relationship between the etiology of refractory childhood epilepsy, CSF neurotransmitters, pterins, and amino acids, and response to a ketogenic diet in 60 patients with refractory epilepsy, 83% focal and 52% idiopathic.
منابع مشابه
Biochemical phenotyping unravels novel metabolic abnormalities and potential biomarkers associated with treatment of GLUT1 deficiency with ketogenic diet
Global metabolomic profiling offers novel opportunities for the discovery of biomarkers and for the elucidation of pathogenic mechanisms that might lead to the development of novel therapies. GLUT1 deficiency syndrome (GLUT1-DS) is an inborn error of metabolism due to reduced function of glucose transporter type 1. Clinical presentation of GLUT1-DS is heterogeneous and the disorder mirrors pati...
متن کاملEffect of Various Levels of Protein in Diet Based on Total and Digestible Amino Acids on Performance of Cobb Strain Broilers
In order to study the effects of various levels of protein in diet based on total and digestible amino acids on performance and carcass traits of broilers, an experiment was conducted as a completely randomized design with 288 broiler chicks from Cobb 500 strain in 6 treatments, each treatment consist of 3 replicates with 16 chicks per replicate. Treatments were the diets as follow: 1) diet for...
متن کاملBranched chain amino acids as adjunctive therapy to ketogenic diet in epilepsy: pilot study and hypothesis.
A pilot prospective follow-up study of the role of the branched chain amino acids as additional therapy to the ketogenic diet was carried out in 17 children, aged between 2 and 7 years, with refractory epilepsy. All of these patients were on the ketogenic diet; none of them was seizure free, while only 13 had more or less benefited from the diet. The addition of branched chain amino acids induc...
متن کاملAssessment and follow up of the children with refractory epilepsy on ketogenic diet
Introduction: The ketogenic diet is a method of treatment that is recommended for patients with epilepsy who have not responded to medications. The present study was designed to evaluate the efficacy of the ketogenic diet along with follow-up on drug resistant epilepsy in children referred to medical centers affiliated to Shiraz University of Medical Sciences. Methods: This study was a multicen...
متن کاملHepatic Fatty Acid Profile of Rats Fed a Triheptanoin-based Ketogenic Diet.
OBJECTIVE the aim of this study was to evaluate the influence of consumption of a ketogenic diet supplemented with triheptanoin, a medium-chain anaplerotic triacylglycerol, on the liver fatty acid profile of Wistar rats. METHODS three groups of male Wistar rats (n = 10) were submitted to an AIN-93 control diet, a triheptanoin- based ketogenic diet, or a soybean oil-based ketogenic diet for 60...
متن کامل